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dc.contributor.authorKomarova, Ekaterina G.-
dc.contributor.authorSharkeev, Yurii P.-
dc.contributor.authorSedelnikova, Mariya B.-
dc.contributor.authorPrymak, Oleg-
dc.contributor.authorEpple, Matthias-
dc.contributor.authorLitvinova, Larisa S.-
dc.contributor.authorShupletsova, Valeria V.-
dc.contributor.authorMalashchenko, Vladimir V.-
dc.contributor.authorYurova, Kristina A.-
dc.contributor.authorDzyuman, Anna N.-
dc.contributor.authorKulagina, Irina V.-
dc.contributor.authorMushtovatova, Lyudmila S.-
dc.contributor.authorBochkareva, Olga P.-
dc.contributor.authorKarpova, Mariia R.-
dc.contributor.authorKhlusov, Igor A.-
dc.date.accessioned2022-04-13T09:23:08Z-
dc.date.available2022-04-13T09:23:08Z-
dc.date.issued2020-09-30-
dc.identifier.urihttps://doi.org/10.3390/ma13194366-
dc.identifier.urihttp://hdl.handle.net/20.500.12701/1972-
dc.description.abstractThis work describes the wettability and biological performance of Zn- and Cu-containing CaP-based coatings prepared by micro-arc oxidation on pure titanium (Ti) and novel Ti-40Nb alloy. Good hydrophilic properties of all the coatings were demonstrated by the low contact angles with liquids, not exceeding 45°. An increase in the applied voltage led to an increase of the coating roughness and porosity, thereby reducing the contact angles to 6° with water and to 17° with glycerol. The free surface energy of 75 ± 3 mJ/m2 for all the coatings were determined. Polar component was calculated as the main component of surface energy, caused by the presence of strong polar PO43− and OH− bonds. In vitro studies showed that low Cu and Zn amounts (~0.4 at.%) in the coatings promoted high motility of human adipose-derived multipotent mesenchymal stromal cells (hAMMSC) on the implant/cell interface and subsequent cell ability to differentiate into osteoblasts. In vivo study demonstrated 100% ectopic bone formation only on the surface of the CaP coating on Ti. The Zn- and Cu-containing CaP coatings on both substrates and the CaP coating on the Ti-40Nb alloy slightly decreased the incidence of ectopic osteogenesis down to 67%. The MAO coatings showed antibacterial efficacy against Staphylococcus aureus and can be arranged as follows: Zn-CaP/Ti > Cu-CaP/TiNb, Zn-CaP/TiNb > Cu-CaP/Ti.ru_RU
dc.language.isoenru_RU
dc.publisherMDPIru_RU
dc.relation.ispartofseriesMaterials;Volume 13, Issue 19-
dc.subjectmicro-arc oxidationru_RU
dc.subjectcalcium phosphate coatingru_RU
dc.subjectTi-40wt.%Nb alloyru_RU
dc.subjectwettabilityru_RU
dc.subjectbiocompatibilityru_RU
dc.subjectectopic bone formationru_RU
dc.subjectbone lamellaeru_RU
dc.subjectantibacterial efficacyru_RU
dc.titleZn- or Cu-containing CaP-Based Coatings Formed by Micro-Arc Oxidation on Titanium and Ti-40Nb Alloy: Part II—Wettability and Biological Performanceru_RU
dc.typeArticleru_RU
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