The European Journal of Medicinal Chemistry is a global journal that publishes studies on the main aspects of medicinal chemistry. It provides a medium for publication of original research papers and also welcomes critical review papers. A typical paper would report on the design (with or without the support of computational methods), organic synthesis, characterization and biochemical/pharmacological evaluation of novel, potent compounds preferentially with a clear (or proven) mechanism of action and/or target. Other topics of interest are molecular aspects of drug metabolism, prodrug synthesis and drug targeting. The journal expects manuscripts to present a clear rational for a study, provide insight into the strategy and design of compounds and into the mechanism of action, and biological targets. Manuscripts reporting only computational studies are out-of-scope unless a new method (broadly applicable, validated and available to the community) is reported. Authors are kindly invited to look to published articles for the scope of the journal and the organisation of papers.